The nucleoids of bacteria and most archaea, as well as the nuclear DNA of eukaryotes, are kept __________ supercoiled.

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The nucleoids of bacteria and most archaea, as well as the nuclear DNA of eukaryotes, are kept negatively supercoiled. This helps to maintain the compact structure of the DNA and also facilitates various DNA-dependent processes such as transcription and replication.

The Nucleoids of Bacteria and Most Archaea, as Well as the Nuclear