The lagging strand is synthesized __________ , while the leading strand can be synthesized __________.

Question

Quizplus · Accepted Answer

The lagging strand is synthesized discontinuously in short fragments called Okazaki fragments. In contrast, the leading strand can be synthesized continuously, as the template strand is oriented in the 3'-to-5' direction and allows for a 5'-to-3' synthesis of the complementary strand. Choice A is incorrect because it describes the opposite of what actually happens. Choice C and D describe the orientation of DNA synthesis, but do not address the discontinuous vs. continuous synthesis of the strands. Choice E is not an accurate description of the process.

The Lagging Strand Is Synthesized __________ , While the Leading