Initiation of DNA replication is controlled by DNA __________ and by the binding of a specific initiator protein to the origin sequence.

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DNA methylation plays a crucial role in the regulation of gene expression, including the initiation of DNA replication. Methylation of DNA can modify the activity of DNA segments without changing the sequence, often serving as a signal for the initiation of DNA replication by affecting the binding of specific proteins to the DNA.

Initiation of DNA Replication Is Controlled by DNA __________ and by the Binding