Actinomycin D is produced by actinomycetes, and it:
A) prevents the mRNA from exiting RNA polymerase
B) prevents binding of RNA polymerase to DNA
C) inhibits transcription in both prokaryotes and eukaryotes
D) binds the beta subunit of RNA polymerase, blocking the exit channel
E) can inhibit translation and replication as well as transcription

Question

Quizplus · Accepted Answer

Actinomycin D inhibits transcription in both prokaryotes and eukaryotes by binding to DNA and preventing RNA polymerase from transcribing the DNA into mRNA. It does not affect translation or replication, and it does not directly interact with RNA polymerase. Therefore, option C is the best choice.

Actinomycin D Is Produced by Actinomycetes, and It