A loss-of-function mutation could NOT be caused by:

Question

Quizplus · Accepted Answer

A loss-of-function mutation refers to a mutation that causes a decrease or loss of gene activity. Silent mutations do not alter the amino acid sequence and, therefore, do not affect the gene product. Thus, they would not lead to a loss of function. Frameshift mutations, nonsense mutations, and insertions can all disrupt the reading frame or protein structure, leading to a loss of function. A knockout mutation is a genetic technique used to intentionally reduce or eliminate the function of a gene, therefore it would definitely cause a loss of function.

A Loss-Of-Function Mutation Could NOT Be Caused By