Which of the following mutants provides the best tools to decipher the genetic pathways of cells?

Question

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Temperature-sensitive mutants can be manipulated to study genetic pathways by allowing normal growth at permissive temperatures and blocking growth or inducing specific phenotypes at restrictive temperatures, thereby providing a way to identify genes involved in specific processes or pathways. Point mutation mutants, nonsense mutation mutants, suppressor ribosome mutants, and RNA polymerase mutants can also be useful tools, but they may not be as versatile as temperature-sensitive mutants in studying genetic pathways.

Which of the Following Mutants Provides the Best Tools to Decipher