All of the following are facts about hepatitis C virus (HCV) EXCEPT:
A) HCV is a (+) strand RNA virus, which requires RNA-dependent RNA polymerases for viral genome replication.
B) Its RNA genome starts with a 5' internal ribosome entry site (IRES) , which facilitates initiation of translation.
C) The HCV virion binds host receptors at or near a tight junction and becomes endocytosed.
D) Host ribosome translates (+) strand RNA to one polyprotein, which is then cleaved to individual HCV proteins in endoplasmic reticulum.
E) New HCV progenies are transferred exclusively through a tight junction to infect other host cells.
Correct Answer:
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