Which of the Following Patients Is Most at Risk for Liver

Which of the following patients is most at risk for liver damage after taking acetaminophen regularly for arthritis pain?

A) Patient with a history of alcohol abuse and hepatitis C
B) Patient with type 2 diabetes and end-stage renal disease
C) Patient with prostate enlargement and urinary frequency
D) Patient with COPD and a 20 pack-year history of smoking