A patient has developed a tolerance to many drugs. The medical definition of the word tolerance is

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Tolerance refers to the capacity to become accustomed to a stimulus or drug. The body adjusts to the effects of the drug and higher and higher doses produce less and less effect. The brain, liver, heart, and other organs can be damaged from the higher drug doses. The word breaks down into the suffix -ance meaning condition, state of, and the root toler- meaning endure.

A Patient Has Developed a Tolerance to Many Drugs