Exhibit 6A This is a reaction going on in your muscle cells right this very minute:
The enzyme triose phosphate isomerase catalyzes this reaction in the forward direction as part of the glycolytic pathway.It follows simple Michaelis-Menten kinetics:
Typical cellular concentrations: triose phosphate isomerase = 0.1 nM
Dihydroxyacetone phosphate = 5 µM glyceraldehyde-3-phosphate = 2 µM
Refer to Exhibit 6A."Hindrate" is an inhibitor of triose phosphate isomerase.When it is added to cells at a concentration of 0.1 nM,the enzyme's KM for the substrate is unchanged,but the apparent Vmax is altered to 50 nM/sec.
In the following graph,which line best represents the Lineweaver-Burk plot obtained in the presence of hindrate?
A) A
B) B
C) C
D) D
E) E
Correct Answer:
Verified
Q29: The Michaelis constant is
A) the rate constant
Q42: The steady state of an enzyme reaction
Q44: The drug acetazolamide:
A) Is used to help
Q50: Exhibit 6A This is a reaction going
Q50: It is important that at physiological conditions,
Q51: The substrate-enzyme (E-S) complex
A) always proceeds to
Q52: Exhibit 6A This is a reaction going
Q56: If the y-intercept of a Lineweaver-Burk plot
Q57: The Michaelis constant determines the Vmax of
Q59: Which of the following statements regarding the
Unlock this Answer For Free Now!
View this answer and more for free by performing one of the following actions
Scan the QR code to install the App and get 2 free unlocks
Unlock quizzes for free by uploading documents