Glutamine synthetase is subject to feedback inhibition by which of the following chemicals?
A) histidine
B) carbamoyl phosphate
C) cytidine triphosphate (CTP)
D) All of these

Question

Quizplus · Accepted Answer

Glutamine synthetase is subject to feedback inhibition by a variety of metabolites, including histidine, carbamoyl phosphate, and cytidine triphosphate (CTP), indicating that all of these chemicals can inhibit its activity. This is a mechanism to regulate the enzyme's activity in response to the cellular levels of these metabolites, ensuring that glutamine synthesis is balanced with the cell's metabolic needs.

Glutamine Synthetase Is Subject to Feedback Inhibition by Which of the Following