Depending on how NADH is shuttled from the cytoplasm into the mitochondria, different molar amounts of ATP will be synthesized as each NADH is oxidized.

Question

Quizplus · Accepted Answer

The amount of ATP synthesized from the oxidation of NADH depends on the shuttle mechanism used to transport NADH from the cytoplasm into the mitochondria. The malate-aspartate shuttle typically results in the production of 2.5 ATP per NADH, while the glycerol phosphate shuttle results in the production of 1.5 ATP per NADH due to differences in how these shuttles interact with the electron transport chain.

Depending on How NADH Is Shuttled from the Cytoplasm into the Mitochondria