Which of the following mechanisms can be used to regulate metabolic pathways?
A) Allosteric activators and inhibitors.
B) Covalent modifications of enzymes.
C) Use of separate enzymes at a given point in the forward and backward pathways.
D) Regulation of the genes for the enzymes used in the pathway.
E) All of these are used to regulate metabolism.

Question

Quizplus · Accepted Answer

All of the options listed (A through D) are mechanisms used to regulate metabolic pathways. Allosteric activators and inhibitors change the activity of enzymes by binding to sites other than the active site. Covalent modifications, such as phosphorylation, can activate or deactivate enzymes. Using separate enzymes for forward and backward reactions allows for independent control of each direction. Regulation of gene expression for enzymes can increase or decrease the amount of enzyme available, thus affecting the pathway's activity.

Which of the Following Mechanisms Can Be Used to Regulate