How do enhancers differ from promoters?
A) Enhancers do not bind RNA polymerase.
B) Enhancers include the UP element.
C) Enhancers bind the sigma (s) factor.
D) There is no difference; these terms are synonymous.

Question

Quizplus · Accepted Answer

Enhancers are DNA sequences that can increase the transcriptional activity of a promoter, but they do not bind RNA polymerase directly. Promoters, on the other hand, are DNA sequences that recruit RNA polymerase to initiate transcription.

Answer: B and C are incorrect. 
 The UP element is a specific sequence found in bacterial promoters that enhances RNA polymerase binding, but it is not typically found in enhancers. Similarly, enhancers do not bind the sigma (s) factor, which is a subunit of RNA polymerase that helps it recognize and bind to promoters.

Answer: D is incorrect. 
 Enhancers and promoters are distinct regulatory elements that have different roles in gene expression. While they can work together to control the level and timing of transcription, they are not interchangeable terms.

How Do Enhancers Differ from Promoters