In eukaryotic replication, the RNA primers are degraded by:
A) the 5' to 3' exonuclease activity of pol ä
B) DNA ligase
C) Helicase
D) FEN-1 and RNase H1

Question

Quizplus · Accepted Answer

In eukaryotic replication, RNA primers are removed by the combined action of FEN-1 (Flap Endonuclease 1) and RNase H1. RNase H1 removes most of the RNA primer, leaving a few ribonucleotides, which are then removed by FEN-1.

In Eukaryotic Replication, the RNA Primers Are Degraded By