Evaluate the ratio M_H+ (pH 3) / M_H+ (pH 7).

Question

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The ratio is determined by the difference in pH and the pKa of the substance involved. The Henderson-Hasselbalch equation can be used to calculate the ratio of protonated to deprotonated forms of a molecule at different pH values. Given a 4 unit difference in pH (from 3 to 7) and assuming the pKa is within this range, each unit difference corresponds to a tenfold change in the concentration of protonated vs. deprotonated forms. Therefore, a 4 unit difference corresponds to a 10,000 fold change in concentration.

Evaluate the Ratio MH+ (PH 3) / MH+ (PH 7)

Evaluate the Ratio M_H+ (PH 3) / M_H+ (PH 7)