The distribution of a drug is determined by

Question

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All of the above choices are correct.If the blood circulation to an organ is low,it will receive less drug.The more membranes and barriers a drug needs to cross,the slower the rate at which it will reach the organ in question.The binding of drugs to plasma proteins reduces the concentration of drug that can leave the circulation and be taken up by an organ.The relative level of fat or water solubility of a drug will influence where and how rapidly a drug will distribute.The distribution of a drug is determined by several factors,such as the size of the organ,the blood flow to the organ,the solubility of the drug,the plasma protein-binding capacity,and the presence of certain barriers (e.g. ,blood-brain barrier,placenta).

The Distribution of a Drug Is Determined by