A dose of a drug that kills 50% of experimental animals is termed

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By definition,the LD₅₀ is the median lethal dose,that is,a dose level that leads to death in 50% of the animals tested.ED₅₀ is the median effective dose,a dose that produces a therapeutic effect in 50% of the subjects tested.A minimally effective dose should not cause death unless death is the desired endpoint.In this case,the incidence of death should be lower to be designated minimal.The therapeutic index is the ratio of LD₅₀ to ED₅₀.

A Dose of a Drug That Kills 50% of Experimental