The direct effect of acetylcholine on the heart is _____ chronotropic and _____ inotropic action.

Question

Quizplus · Accepted Answer

Acetylcholine produces a negative chronotropic (reduced rate)and negative inotropic (force)of heart contraction.Cholinergic agents are classified as direct acting (acts on receptor)or indirect acting (causes release of neurotransmitter).The direct-acting agents include the choline derivatives and pilocarpine.The choline derivatives include both acetylcholine and other,more stable choline derivatives.A decrease in cardiac output is associated with these agents.

The Direct Effect of Acetylcholine on the Heart Is _____