Alcohol consumption stimulates the breakdown of acetaminophen,thereby decreasing the toxic potential of acetaminophen use.

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Depending on the amount of alcoholic beverages consumed,the maximum dose of acetaminophen varies.The normal maximum dose of acetaminophen (4 g)may be used in patients who usually do not drink alcohol.The dose should be restricted to 2 g if a patient is a moderate drinker (less than three alcohol beverages daily).Alcohol stimulates the oxidizing enzymes that metabolize acetaminophen to its toxic metabolite.In this way,it increases acetaminophen toxicity.

Alcohol Consumption Stimulates the Breakdown of Acetaminophen,thereby Decreasing the Toxic