Morphine has its most potent action on the _____ class of opioid receptors,and pentazocine has its most potent action on the _____ class of opioid receptors.

Question

Quizplus · Accepted Answer

The three opioid receptors that have been characterized in more detail and that are stimulated by the opioids are the mu,kappa,and delta receptors.Other opioid receptors include sigma and epsilon.Stimulation of sigma receptors is associated with autonomic stimulation,dysphoria,hallucinations,nightmares,and anxiety.It is thought that stimulation of epsilon receptors may result in analgesia.Morphine is a mu-receptor agonist,and pentazocine is a kappa-receptor agonist.Stimulation of mu receptors produces analgesia.Stimulation of kappa receptors produces dysphoria.Morphine has no effect on the kappa receptor and produces less dysphoria than pentazocine.Pentazocine is a kappa receptor agonist that produces dysphoria.

Morphine Has Its Most Potent Action on the _____ Class