Aminoglycosides

Question

Aminoglycosides

Quizplus · Accepted Answer

Aminoglycosides are used primarily to treat aerobic gram-negative infections when other agents are ineffective.They have little action against gram-positive anaerobic or facultative bacteria.The aminoglycosides are bactericidal.Because they have little action against gram-positive anaerobic or facultative bacteria,aminoglycosides would not be the drug of choice for treatment of a stage 1 infection.Rather,the drug of choice in patients without a penicillin allergy is penicillin V 500 mg every 6 hours for 5 to 7 days.Aminoglycosides appear to inhibit protein synthesis and to act directly on the 30S subunit of the ribosome.