The sulfonamides competitively inhibit the bacterial enzyme that incorporates para-aminobenzoic acid (PABA)into an immediate precursor of

Question

Quizplus · Accepted Answer

Because of their structural similarity to PABA,the sulfonamides competitively inhibit dihydropteroate synthetase,the bacterial enzyme that incorporates PABA into dihydrofolic acid,an immediate precursor of folic acid.Unlike humans,many bacteria are unable to use preformed folic acid,which is essential for their growth.They must synthesize folic acid from PABA.The other choices are not derived from para-aminobenzoic acid.

The Sulfonamides Competitively Inhibit the Bacterial Enzyme That Incorporates Para-Aminobenzoic