Each of the following will have the action prolonged and toxicity increased by allopurinol,which is used to prevent hyperuricemia,except one.Which is the exception?

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The treatment of leukemia and lymphomas often results in rapid tumor destruction with a consequent high uric acid level.Allopurinol is a xanthine oxidase inhibitor used in the management of gout.Allopurinol is administered to prevent hyperuricemia before the initiation of a regimen of antineoplastic agents that release purines and pyrimidines.Allopurinol decreases the metabolism and clearance of azathioprine and mercaptopurine,and increases the toxicity of cyclophosphamide.It does not enhance the toxicity of 5-fluorouracil.

Each of the Following Will Have the Action Prolonged and Toxicity