The nurse recognizes that patients with which conditions will have a reduction in the distribution of drugs? (Select all that apply. )
A)Peripheral vascular disease
B)Heart failure
C)Liver disease
D)Obesity

Question

Quizplus · Accepted Answer

The rate and extent of distribution depend on circulation,cell membrane permeability,and protein binding.Peripheral vascular disease and heart failure result in a decrease in circulation,which reduces distribution.Liver disease causes a reduction in plasma proteins,which results in more free active drug that is distributed more readily.Obesity does not affect distribution.

The Nurse Recognizes That Patients with Which Conditions Will Have