Following topical administration of a drug,the drug form does not need to undergo disintegration as it quickly dissolves in the tissue fluids of the skin.

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Topical drugs are designed to be applied directly to the skin or mucous membranes for localized therapeutic effects. Since the drug form quickly dissolves in the tissue fluids of the skin, there is no need for it to undergo disintegration. However, some topical drugs may require the use of penetration enhancers or other vehicles to promote absorption into the skin.

Following Topical Administration of a Drug,the Drug Form Does Not