The Same Drug Given by a Different Route Can Exert

The same drug given by a different route can exert either a local or a systemic effect.An example of this is ________.

A) topical Benadryl that relieves skin itching and oral Benadryl that relieves skin itching, nasal stuffiness, and red, watery eyes
B) an antihistamine drug that, when taken with grapefruit juice, can cause the adverse effect of heart arrhythmias
C) topical lidocaine that is gargled for anesthesia in the mouth and intravenous lidocaine that is used to treat cardiac arrhythmias
D) A and C