Solid-phase extraction is a sample preparation technique.Which of the following statements is(are)NOT true for an aqueous solid-phase extraction?
I Solid-phase extraction separates analyte from the sample matrix using a chromatography stationary phase.
II An aliquot of the aqueous sample is applied to the solid-phase extraction tube,washing the sample with additional sample and then a water wash.
III The analyte sticks to the column and the water wash removes all species that do not adhere to the column.
IV An organic solvent is used to wash the analyte from the column.
V The organic phase containing the analyte is evaporated to dryness and the solid is dissolved in water,ready for analysis.
A)III
B)I
C)II and III
D)IV
E)II

Question

Quizplus · Accepted Answer

The statement II is incorrect because the sample is not washed with additional sample; instead, it is typically washed with a solvent or buffer to remove impurities.

Solid-Phase Extraction Is a Sample Preparation Technique