Although small hairpin RNAs are used in RNAi-mediated destruction of a target mRNA,in order for them to be effective,the double-stranded RNA must be cleaved by which of one of the following?

Question

Quizplus · Accepted Answer

Dicer is the enzyme responsible for cleaving the double-stranded RNA into small interfering RNAs (siRNAs) or microRNAs (miRNAs) during RNA interference (RNAi). RISC (RNA-induced silencing complex) is then responsible for recognizing and degrading the target mRNA. RNA polymerase is involved in transcription, while exonucleases are involved in degrading RNA molecules.

Although Small Hairpin RNAs Are Used in RNAi-Mediated Destruction of a Target