You are studying the regulation of a group of genes and have determined that the full activation of transcription of these genes occurs when histone acetyl transferases have made post-translational modifications specifically to which one of the following amino acids?
A)glycine
B)glutamine
C)lysine
D)proline

Question

Quizplus · Accepted Answer

Histone acetyl transferases (HATs) catalyze the addition of acetyl groups to lysine residues within histone proteins. This neutralizes the positive charge of lysines and loosens the interactions between histones and DNA, allowing for easier access to the genes and facilitating their transcriptional activation. Therefore, the full activation of transcription of these genes requires HATs to modify specific lysine residues.

You Are Studying the Regulation of a Group of Genes