Which of the following lines of evidence is indicative of the presence of a gene in an unknown DNA sequence?
A)alignment to a partial cDNA sequence
B)sequence similarity to genes of other organisms
C)ORF consistent with the rules for exon and intron sequences
D)all of the above

Question

Quizplus · Accepted Answer

All three lines of evidence - alignment to a partial cDNA sequence, sequence similarity to genes of other organisms, and ORFs consistent with the rules for exon and intron sequences - are indicative of the presence of a gene in an unknown DNA sequence. The presence of any one of these lines of evidence should lead to further investigation to confirm the presence of a gene.

Which of the Following Lines of Evidence Is Indicative of the Presence