A transmembrane receptor that functions at the cell membrane has an exoplasmic N-terminal sequence,a signal-anchor sequence,and a stop-transfer-anchor sequence.This protein was first inserted into the membrane where?

Question

Quizplus · Accepted Answer

The presence of a signal-anchor sequence and a stop-transfer-anchor sequence indicate that the protein was inserted into the membrane via the endoplasmic reticulum (ER). Additionally, transmembrane receptors are often synthesized and inserted into the ER membrane before being transported to their final destination, making the ER the most likely location for initial membrane insertion.

A Transmembrane Receptor That Functions at the Cell Membrane Has