Muscarinic acetylcholine receptors are GPCRs that slow the rate of heart muscle contraction upon ligand binding/activation.Activation of this receptor leads to opening of potassium channels triggered by decreases in cAMP levels.The muscarinic acetylcholine receptor likely couples to:

Question

Quizplus · Accepted Answer

The opening of potassium channels triggered by decreases in cAMP levels is mediated by Gαi. Therefore, the muscarinic acetylcholine receptor likely couples to Gαi.

Muscarinic Acetylcholine Receptors Are GPCRs That Slow the Rate of Heart