Serum response factor (SRF)is phosphorylated by:
A)MEK.
B)MAP kinase.
C)p90ᴿˢᴷ.
D)Raf.
E)Ras.

Question

Quizplus · Accepted Answer

SRF is predominantly phosphorylated by p90ᴿˢᴷ, also known as p90 ribosomal S6 kinase. While other kinases like MAP kinase and Raf can also phosphorylate SRF, p90ᴿˢᴷ is the main kinase responsible for SRF phosphorylation. MEK is an upstream kinase of MAP kinase and Ras activates a pathway that leads to MAP kinase activation, but neither directly phosphorylates SRF.

Serum Response Factor (SRF)is Phosphorylated By