Which of the following is a G-actin sequestering protein that allows cells to maintain a relatively high G-actin concentration in cells?
A)thymosin β₄
B)FH2 domain of formin
C)profilin
D)cofilin

Question

Quizplus · Accepted Answer

Thymosin β₄ is a G-actin sequestering protein that binds to G-actin and prevents its polymerization into F-actin, thereby allowing cells to maintain a relatively high G-actin concentration in cells. Profilin also binds to G-actin and promotes F-actin assembly, but it does not sequester G-actin. FH2 domain of formin and cofilin are both involved in actin polymerization and regulation, but they do not sequester G-actin.

Which of the Following Is a G-Actin Sequestering Protein That