Separation of spindle poles during spindle formation and anaphase B most likely depends on which of the following?
A)(+)end-directed microtubule motors at the cell cortex
B)(+)end-directed microtubule motors at the kinetochore
C)(−)end-directed microtubule motors in the microtubule overlap zone
D)(+)end-directed microtubule motors in the microtubule overlap zone

Question

Quizplus · Accepted Answer

During spindle formation and anaphase B, the separation of spindle poles is driven by (+)end-directed microtubule motors in the microtubule overlap zone. These motors slide the microtubules past each other and push the poles apart. (-)end-directed motors play a role in positioning the spindle and maintaining its stability, but they do not contribute to pole separation. Motors at the cell cortex and kinetochores are involved in different aspects of spindle assembly and function, but not in pole separation specifically.

Separation of Spindle Poles During Spindle Formation and Anaphase B