What signal is released by endothelial cells to recruit circulating leukocytes?
A)Vesicle-sequestered P-selectins are moved to the cell surface.
B)Vesicle-sequestered αL β2 molecules are moved to the cell surface.
C)Integrins are cleaved from the plasma membrane so that the extracellular domain can bind leukocytes.
D)Secreted glycoproteins trigger leukocytes to initiate "rolling" motility.

Question

Quizplus · Accepted Answer

Vesicle-sequestered P-selectins are moved to the cell surface to bind to glycoproteins on circulating leukocytes, initiating the process of "rolling" motility and ultimately recruitment of leukocytes to the site of inflammation or injury.

What Signal Is Released by Endothelial Cells to Recruit Circulating