Which of the following provides evidence for the role of Paneth cells in supporting the intestinal stem cell niche?

Question

Quizplus · Accepted Answer

A) Mutant mice with reduced numbers of Paneth cells have fewer intestinal stem cells, providing evidence for the importance of Paneth cells in the intestinal stem cell niche.
B) Co-culture of Paneth cells with intestinal stem cells leads to formation of villus-like structures, further supporting the idea that Paneth cells are involved in supporting the stem cell niche.
C) Paneth cells produce Wnt, which is a key signaling molecule in the intestinal stem cell niche, and therefore provides further evidence for the role of Paneth cells in supporting this niche.

Which of the Following Provides Evidence for the Role of Paneth