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Somatic Recombination Is Catalyzed by RAG1 and RAG2 Recombinases

Question 13

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Somatic recombination is catalyzed by RAG1 and RAG2 recombinases.How does the RAG1-RAG2 complex recognize the cleavage site at the exact boundary of the coding and signal sequences in the variable regions of immunoglobulin genes?

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At the 3´ end of each light-chain V gene...

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