Hereditary cancers typically possess loss-of-heterozygosity in:

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Hereditary cancers typically possess loss-of-heterozygosity in tumor-suppressor genes, which are responsible for regulating cell division and preventing tumor formation. Proto-oncogenes, on the other hand, can become oncogenes when they are mutated or overexpressed, promoting uncontrolled cell growth and potentially leading to cancer, but loss-of-heterozygosity in proto-oncogenes is not a common feature of hereditary cancers.

Hereditary Cancers Typically Possess Loss-Of-Heterozygosity In