How does obesity act as an important risk factor for type 2 diabetes mellitus?

Question

Quizplus · Accepted Answer

Obesity is associated with increased resistance to insulin by cells, which means that cells are less responsive to insulin and the pancreas has to produce more insulin to enable glucose uptake by cells. This increased demand on the pancreas can eventually lead to beta cell fatigue and impaired insulin secretion, resulting in the development of type 2 diabetes mellitus.

How Does Obesity Act as an Important Risk Factor for Type