What is the pathogenesis of polycystic ovarian syndrome?
A) A decrease in leptin levels reduces the hypothalamic pulsatility of gonadotropin releasing hormone,which reduces the number of follicles that mature
B) A disorder in the anterior pituitary increases the follicle-stimulating hormone,which reduces the luteinizing hormone released
C) Hyperinsulinemia affects follicular decline by suppressing apoptosis,enabling follicles,which normally disintegrate to survive
D) Testosterone stimulates androgen secretion by the ovarian stroma and reduces sex hormone-binding globulin indirectly

Question

Quizplus · Accepted Answer

Polycystic ovarian syndrome (PCOS) is characterized by hyperinsulinemia, which affects follicular decline by suppressing apoptosis, enabling follicles that normally disintegrate to survive. This results in the development of multiple cysts on the ovaries. The other options are not accurate descriptions of the pathogenesis of PCOS.

What Is the Pathogenesis of Polycystic Ovarian Syndrome