How does hemolytic disease of the newborn (HDN)cause acquired congenital hemolytic anemia?
A) HDN develops when hypoxia or dehydration cause the erythrocytes to change shapes,which are then recognized as foreign and removed from circulation.
B) HDN is an alloimmune disease in which the mother's immune system produces antibodies against fetal erythrocytes,which are recognized as foreign and removed from circulation.
C) HDN develops when the polycythemia present in fetal life continues after birth causing the excessive number of erythrocytes to be removed from circulation.
D) HDN is an autoimmune disease in which the fetus' immune system produces antibodies against fetal erythrocytes,which are recognized as foreign and removed from circulation.

Question

Quizplus · Accepted Answer

Hemolytic disease of the newborn (HDN) is an alloimmune disease that occurs when the mother's immune system produces antibodies against fetal erythrocytes that are different from her own. These antibodies can cross the placenta and cause destruction of fetal erythrocytes, leading to anemia in the fetus. If this anemia is severe and prolonged, it can result in acquired congenital hemolytic anemia in the newborn.

How Does Hemolytic Disease of the Newborn (HDN)cause Acquired Congenital