Why does hypertension occur in acute poststreptococcal glomerulonephritis (PSGN)?
A) Because of the increase in capillary permeability along the glomerular vascular membrane.
B) Because of the release of endothelin-1 as a result of endothelial injury and platelet activation.
C) Because of the activation of the renin-angiotensin-aldosterone system stimulated by decreased renal perfusion.
D) Because of the stimulation of a-adrenergic nerves that cause vasoconstriction.

Question

Quizplus · Accepted Answer

In acute poststreptococcal glomerulonephritis (PSGN), hypertension occurs due to the release of endothelin-1 as a result of endothelial injury and platelet activation. This leads to vasoconstriction of the renal arterioles, resulting in an increase in blood pressure.

Why Does Hypertension Occur in Acute Poststreptococcal Glomerulonephritis (PSGN)