Considering the pathophysiology of osteoporosis, which hormone exerts antiapoptotic effects on osteoblasts, but proapoptotic effects on osteoclasts?
A)Parathyroid hormone
B)Glucocorticoid
C)Growth hormone
D)Estrogen

Question

Quizplus · Accepted Answer

Data reveal that sex steroids (e.g., estrogens) exert antiapoptotic effects on osteoblasts but exert proapoptotic effects on osteoclasts; in both scenarios this is accomplished by activating the extracellular signal regulated kinases (ERKs).

Considering the Pathophysiology of Osteoporosis, Which Hormone Exerts Antiapoptotic Effects