Which protein,present in normal muscle cells and absent in muscle cells of Duchenne muscular dystrophy,mediates the anchoring of skeletal muscles fibers to the basement membrane?
A) Syntrophin
B) Laminin
C) Dystrophin
D) Troponin

Question

Quizplus · Accepted Answer

Dystrophin is the protein that anchors muscle fibers to the basement membrane, and its absence in Duchenne muscular dystrophy leads to muscle degeneration and weakness. Syntrophin is a component of the dystrophin-associated protein complex (DAPC) and is involved in regulating ion channels in muscle cells. Laminin is a major component of the basement membrane, but it is not specifically involved in mediating the anchoring of muscle fibers to the basement membrane. Troponin is a protein involved in muscle contraction, but it is not related to anchoring muscle fibers to the basement membrane.

Which Protein,present in Normal Muscle Cells and Absent in Muscle