Which skin lesion is mediated by immunoglobulins E (IgE)-stimulated release of histamine,bradykinin,kallikrein,or acetylcholine from mast cells?
A) Dermatitis
B) Scleroderma
C) Urticaria
D) Cutaneous vasculitis

Question

Quizplus · Accepted Answer

Urticaria, also known as hives, is a type of skin rash that is characterized by the sudden appearance of pale red, raised and itchy wheals or welts on the skin. It is usually caused by immunoglobulin E (IgE)-stimulated release of histamine, bradykinin, kallikrein or acetylcholine from mast cells, which leads to inflammation and dilation of blood vessels in the skin. This results in the characteristic redness, swelling and itching of urticarial lesions.

Which Skin Lesion Is Mediated by Immunoglobulins E (IgE)-Stimulated Release