In secondary multiple organ dysfunction syndrome (MOSD) ,what stimulates the normal endothelial cells to change to proinflammatory state?
A) Interleukin 4 (IL-4) and interleukin 13 (IL-13)
B) Interleukin 1 (IL-1) ,interleukin 6 (IL-6) ,and tumor necrosis factor alpha (TNF-)
C) Interferon gamma and granulocyte cell-stimulating factor
D) Prostaglandin,leukotrienes,histamine,and bradykinin
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