What stimulates the "respiratory burst" and production of highly toxic free radicals in multiple organ dysfunction syndrome (MOSD)?

Question

Quizplus · Accepted Answer

Neutrophils adhering to the endothelium can stimulate the "respiratory burst" and production of highly toxic free radicals in MOSD. This is because the neutrophils, sensing an infection or injury, release reactive oxygen species as part of the immune response, leading to oxidative stress and tissue damage. The accumulation of damaged tissue can manifest as multiple organ dysfunction syndrome. The other choices (B, C, and D) may also play a role in the pathogenesis of MOSD, but do not directly stimulate the respiratory burst and production of free radicals.

What Stimulates the "Respiratory Burst" and Production of Highly Toxic