Match the term with the appropriate description.

-Prozone phenomenon

Question

Match the term with the appropriate description.

-Prozone phenomenon

Quizplus · Accepted Answer

The prozone phenomenon is an excessive concentration of antibody that leads to a false-negative reaction.

Answer: C
 The zone in which no lattice formation occurs is the prozone, which is caused by an excess of antigen.

Answer: A and D
 The optimum zone for precipitation occurs when there is an equal amount of antigen and antibody concentrations (D). However, some sources use the term prozone to refer to the incomplete zone that occurs before the optimum zone, where there is not enough antigen or antibody for lattice formation. In this case, the prozone phenomenon (B) refers to the false-negative reaction that can occur with an excessive concentration of antibody.

Match the Term with the Appropriate Description